For information on
website advertising,
please contact the PCOSA's
IT Department:
it@pcosupport.org

Research Study Directory

If you know of any research studies that need to be added to this page, please fill out our online form. Remember to include all pertinent information including what the study is for, what the primary inclusion criteria are and any conditions that would exclude women from participating.
Please note: information for each study is provided by those conducting it. The PCOSA is not responsible for the accuracy of contact information, or any other information provided in this directory. If you find an entry which is inaccurate, or is for a study which has been completed, please e-mail webmistress@PCOSupport.org.

Click on the state name below to access the studies in your area.

U. S. A. Nationwide Studies

Are you a Woman with Infrequent Menstrual Periods or Polycystic Ovary Syndrome?

There are several studies being conducted at the Hershey Medical Center under the direction of Dr. Richard Legro, MD Division of Reproductive Medicine, OBGYN. These studies have been approved by the Institutional Review Board under FDA regulations, at Penn State College of Medicine, Hershey, PA

Genetics of PCOS
Women between the ages of 18 and 40 without serious health problems with 6 or fewer menstrual periods per year may be eligible to participate in a research study. You cannot be taking birth control pills or other hormones to be in the study.The study is nationwide and will involve diagnostic testing and medical evaluation at no charge. You will receive a stipend The study is under the direction of Dr. Richard Legro of the Department of OB/GYN.
For more information please contact:
bscheetz@psu.edu
Dept of OB/GYN
Penn State Hershey Medical Center
Hershey, PA 17022
Website: http://www.hmc.psu.edu/womens/research/pcos/index.html 1-800-585-9585 or 717-531-4483
End Date: 3/1/07

Summary:
This study is aimed at gathering information about how people are using Internet services to improve the quality of their well-being. The questionnaire is not aimed at obtaining detailed information about the issues women are seeking help with. No personal information (i.e. names or mailing addresses) will be requested. My intention is to gather information about how people are using their computer to help them with a troubling syndrome. To participate in my study please click the secure link below for further information. http://www.webcitypress.com/survey

Principal Investigators:

Maria Ann Brooks, M.A.

Time Requirements:

The questionnaire will take 30-45 minutes of your time.

Contact Person for Questions Involving this Study:

If you have any questions regarding this study, you may contact: Maria Brooks M.A., Mbrooks@alliant.edu or Lillian Harrison PhD, Lharrison@alliant.edu.

Ms. Maria Ann Brooks
5130 East Clinton Way
Fresno, CA 93727
559-456-2777

Summary:
Determining the Familial Contribution in Subsets of PCOS. This study is to investigate if PCOS is an inherited disorder. In order to determine what difference, if any, exists in the clinical features or the DNA of a woman with PCOS, we also need to look at the clinical features and the DNA of their relatives and at normal women controls and their relatives for comparison.

Requirements:
Woman Age 18 and up
PCOS and Normal Volunteers

Costs and/or compensation:
All of the procedures will be free of charge

Comments:
You don't need to be a MA resident to participate.

Contact information:
Mrs. Yarisie Jimenez
55 Fruit St BHX-5
Boston, MA 02114
Phone: 617-726-5526
Fax: 617-726-9150
E-mail Address: YJimenez@partners.org

Irregular Periods or PCOS?
Do you have 6 or fewer periods per year or a previous diagnosis of PCOS?
Are you 18-45 years of age?
Are you not on oral contraceptives?
Have a BMI of 25 or less? (see BMI chart below)

If you answered YES to all of these questions, then you and your family may qualify to participate in a genetics study of PCOS. You do not need to live near the Chicago area to participate. We will make arrangements for all medical testing to be done at a hospital near you, and we will pay for blood drawing and shipping. There will be no cost to participants.

The study is under the direction of Dr. Andrea Dunaif, Chief of the Division of Endocrinology, Metabolism, and Molecular Medicine at Northwestern University Medical School.
For details call 1-800-847-6060 or e-mail pcos@northwestern.edu

PDF Version of BMI Chart

Alabama

Summary: Could You Have PCOS?

Requirements:
If you are between 18 to 40 years old and have more than one of the following
- Fewer than 6 menstrual periods a year
- Increased coarse hair on the face
- Excessive weight gain, especially over mid section
- Balding of the scalp
- Glucose/ insulin problems
- High Blood pressure or acne/ skin problems
You may be eligable for a research study for women with Polycystic Ovary Syndrome

Start date for study: Enrolling now

Contact information:
Ms. Cindy Jones
1758 Park Place, Apt #: 200
Montgomery, AL 36106
Phone: 334-265-3300
Fax: 334-265-2704
E-mail Address: cjones@drugresearch.com
Drug Research and Analysis Corporation (1-800-DRACNOW)

Alaska

Arizona

If you have irregular menstruation, infertility, and/or excess body hair, you may be eligible to participate in a physician supervised research study to evaluate the effectiveness of an investigational medication for Polycystic Ovary Syndrome.

You may be eligible to participate in this study if you:

• Are between 18 and 45 years of age
• Have irregular menstrual periods
• Have excess facial or body hair

Qualified participants will receive the following study related benefits at no cost:

• Physical examination
• Electrocardiogram
• Ultrasound
• Laboratory tests
• Study medication for 8 weeks
• Up to $210 compensation for time and travel

All individuals who participate must be willing and able to comply with the study, and must sign a study specific informed consent.

Contact:
Study Coordinator
ACRC/Arizona Clinical Research Center
5656 East Grant Road, Suite 450
Tucson, AZ 85712
Telephone: 520-290-9896
Fax: 520-290-2508
Email: acrc@futureone.com

Arkansas

California

Title: The effects of polyunsaturated and monounsaturated fatty acids on insulin resistance in women with PCOS.

Summary: This study is a clinical trial involving women with PCOS being conducted at the University of California, Davis in Sacramento, California. The aim is to investigate the effects of dietary fatty acids on glucose homeostasis. Women with PCOS have insulin resistance which leads to excess hair growth and infertility. There are medications that improve insulin resistance, however the long term effects of these are unknown. We propose to use dietary poly and monounsaturated fatty acids, including almonds, walnuts, walnut oil and fish oil in order to treat the adverse effects of PCOS.

Requirements for Participation:
The clinical trial will last for a total of ten weeks, six weeks being an intervention phase. The intervention will consist of taking almonds, walnuts, walnut oil or fish oil on a daily basis. The participants will undergo four glucose tolerance tests throughout the six week intervention phase. Due to the number of glucose tolerance tests that need to be completed, we request that study participants live within driving distance of Sacramento, California.

Inclusion criteria:
-Age 18-45
-Diagnosis of PCOS

Exclusion criteria:
-Use of oral contraceptives, insulin sensitizers, dietary supplements (need to be stopped 2months prior to the trial)
-Diabetes mellitus or any systemic illness including kidney or liver disease

Costs/Compensation:
Participants will need to provide their own travel to and from our Clinical Resource Center in Sacramento, California. Monetary compensation will be given to each participant for travel.

Date Study begins: ongoing enrollment
Date Study ends: 2008

Contact Information:
Sharan Gill, M.D.
University of California Davis Medical Center
4150 V. Street, suite G400
Sacramento, CA 95817
Phone: (916)734-3903
Fax: (916) 734-7953
Email: pcos_study@yahoo.com

Colorado

Connecticut

Delaware

District of Columbia

Florida

Georgia

Hawaii

Idaho

If you are between 18 to 40 years old and have more than one of the following:

• Fewer than 6 menstrual periods a year
• Increased hair on face and body
• Excessive weight gain, especially over mid section
• Loss of hair
• Glucose/insulin problems
• High blood pressure or acne/skin problems

Please Contact:
AmericasDoctor
Located in:
Boise, ID 83706
Telephone: 208-345-6213

Illinois

Summary:
Are you a woman with Irregular Periods or Polycystic Ovary Syndrome?

Requirements:
Northwestern University Medical School invites women with 6 or fewer periods per year, or a previous diagnosis of PCOS, who are ages 18-40 years, and not on oral contraceptives, to participate in a research study investigating the relationship between ovarian hormones and insulin.

Costs and/or compensation
The study involves up to 4 visits to our research center. If qualified, you may receive:
- a no cost diabetes screening
- a stipend for participating

The study is under the direction of Dr. Andrea Dunaif, Chief of the Division of Endocrinology, Metabolism, and Molecular Medicine.

Contact information:
Study Coordinator
303 East Chicago Avenue
Tarry 15-716
Chicago, IL 60611
Phone: 1-800-847-6060
E-mail Address: pcos@northwestern.edu

Irregular Periods or PCOS?
Do you have 6 or fewer periods per year or a previous diagnosis of PCOS?
Are you 18-45 years of age?
Are you not on oral contraceptives?

If you answered YES to all of these questions, then you and your family may qualify to participate in a genetics study of PCOS. You do not need to live near the Chicago area to participate. We will make arrangements for all medical testing to be done at a hospital near you, and we will pay for blood drawing and shipping. There will be no cost to participants.

The study is under the direction of Dr. Andrea Dunaif, Chief of the Division of Endocrinology, Metabolism, and Molecular Medicine at Northwestern University Medical School.
For details call 1-800-847-6060 or e-mail pcos@northwestern.edu

Randy S. Morris, MD

We have an opportunity for women with ovulation problems that are currently attempting to become pregnant to enroll in a study evaluating a new type of fertility medication.

Study Title

A Phase II Prospective, Randomized, Double Blind, Placebo-Controlled, Multicenter, Dose Finding, Comparative Study for the evaluation of the Aromatase Inhibitor Anastrozole (Multiple Dose) versus Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile women with Ovulatory Dysfunction.

Study Objectives

Primary
To evaluate the safety and tolerability of anastrozole over a range of doses and to determine the most effective dose to induce follicular maturation in infertile women with ovulatory dysfunction.

Secondary
To determine whether there are differences in the safety, tolerability or effectiveness depending on the type of ovulatory dysfunction.


Initial eligibility criteria :

• Age 18-35 inclusive
• Infertility and currently trying to achieve pregnancy
• Body Mass Index (BMI) is less than 35 kg/m2. Click here to determine your BMI
• Ovulatory Dysfunction as defined by one of the following:
         Subject's usual cycle length is less than 21 or greater than 35 days with at least 6 menses per year.
         Subject’s cycle length is > 35 days with less than 6 menses per year.
• Two fallopian tubes without blockage
• Two functional ovaries
• No previous gonadotropin treatments (like Gonal F, Follistim, Pergonal, Repronex)
• No more than six previous clomiphene citrate cycles overall or 6 non-ovulatory clomiphene cycles
• Non smoker or less than 5 cigarettes per day
• Normal PAP smear in the last 6 months
• Male partner has had a semen analysis within last 6 months acceptable for achieving pregnancy with intercourse.

• Three or more consecutive pregnancy losses
• Known infection with HIV/AIDS, Hepatitis B or Hepatitis C
• Current or recent pregnancy
• Any contraindication to pregnancy
• Enrollment in any other study within 4 weeks of starting this study
• Taking certain medications that affect the metabolism of the study medication
• Use of fertility medication within 4 weeks of starting this study

Prospective: This study is collecting data as an ongoing process as compared to analyzing data that was collected in the past.
Randomized: There will be different study groups and participants will be placed into these groups at random. In other words any participant could be placed into any group.
Double Blind: The participants will take different types or doses of medication. Neither the participant nor the doctor conducting the investigation will know who is taking what until after the study is over.
Placebo controlled: Since there are different dose groups, some of the pills given will not contain any active medication. This is so that everyone will always take the same number of pills each day and no one will know what dose they are on.
Multicenter: The study is being conducted at more than one location
Dose finding: One purpose of the study is to find the optimal dose of medication for future use.
Aromatase inhibitor: Aromatases the enzyme the body needs to form estrogens. An aromatase inhibitor blocks the effects of that enzyme resulting in less production of estrogens.
Clomiphene citrate: An oral fertility medication that has been in use for over forty years.
Follicular Growth: Human eggs grow inside of tiny cysts called follicles. Fertility medications are used to stimulate follicular (and hence egg) growth.
Ovulation: The release of the egg from the follicle.
Ovulatory dysfunction: Any disturbance in a woman’s normal reproductive system that results in eggs not being released or not being released on a regular pattern.

Indiana

Iowa

Kansas

Kentucky

Louisiana

Maine

Maryland

Massachusetts

Summary:
Determining the Familial Contribution in Subsets of PCOS. This study is to investigate if PCOS is an inherited disorder. In order to determine what difference, if any, exists in the clinical features or the DNA of a woman with PCOS, we also need to look at the clinical features and the DNA of their relatives and at normal women controls and their relatives for comparison.

Requirements:
Woman Age 18 and up
PCOS and Normal Volunteers

Costs and/or compensation:
All of the procedures will be free of charge

Comments:
You don't need to be a MA resident to participate.

Contact information:
Mrs. Yarisie Jimenez
55 Fruit St BHX-5
Boston, MA 02114
Phone: 617-726-5526
Fax: 617-726-9150
E-mail Address: YJimenez@partners.org

Summary:
The study is a Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Clinical Study, using a combination of a new investigational drug and Clomid in women with PCOS. This is an ovulation induction study.

Requirements:
Woman between the age of 18-40 years old
Irregular Menstrual Cycles
Are not on any Hormone Medications or Insulin sensetizers
Acne and/or Excessive Hair Growth

Costs and/or compensation:
Volunteers will be remunerated up to $200

Contact information:
Mrs. Yarisie Jimenez
55 Fruit St BHX-5
Boston, MA 02114
Phone: 617-726-5526
Fax: 617-726-9150
E-mail Address: YJimenez@partners.org

The purpose of the study is to identify the role of insulin in abnormal pituitary hormone release in women with Polycystic Ovarian Syndrome (PCOS) and in heathy volunteers. The information from these studies will be extremely important in understanding certain kinds of abnormalities of reproductive hormones.

Patient Inclusion/Exclusion Criteria:

Womens ages 18 to 40
Irregular Menstrual Cycles (fewer than nine per year)
Acne and/ or excess hair growth
(also known as Polycystic Ovarian Syndrome)
On no hormonal medication
Remuneration available up to $500

Contact:
Yarisie Jimenez BS
Massachusetts General Hospital
Fruit Street
Boston, MA 02115
Telephone: 617-726-5526
Email: yjimenez@partners.org

Michigan

Minnesota

Mississippi

Missouri

Montana

Nebraska

Nevada

New Hampshire

New Jersey

New Mexico

New York

Summary: Adolescent girls ages 12-18 years, with Polycystic Ovary Syndrome (PCOS) are being actively recruited to assess the metabolic impact of intensive lifestyle modification, oral contraceptives, metformin and placebo on the symptoms of PCOS. Study subjects must have an irregular menstrual cycle and be overweight and/or physical evidence of androgen excess (acne or facial hair). Enrollment of 40 adolescent girls for this 24 week pilot study.

Requirements: Adolescent girls, ages 12-18, irregular menstrual cycles, overweight.

Costs and/or compensation: $200.00 for completion of study Country: United States

Start date for study: May 2006
End date for study: when enrollment complete

Contact information:
Ms. Lynda Kochman, RN, CCRC
University of Rochester Medical Center
601 Elmwood Ave, Box 668
Rochester, NY 14642
Country: United States

Phone: 585-273-2995
Fax: 585-276-2244
E-mail Address: Lynda_Kochman@urmc.rochester.edu

Comments: Study participants will need to live near the Rochester, NY area as regular visits to Rochester are required as a part of the study.

North Carolina

North Dakota

Ohio

Oklahoma

Oregon

Pennsylvania

Are you a Woman with Infrequent Menstrual Periods or Polycystic Ovary Syndrome?

There are several studies being conducted at the Hershey Medical Center under the direction of Dr. Richard Legro, MD Division of Reproductive Medicine, OBGYN. These studies have been approved by the Institutional Review Board under FDA regulations, at Penn State College of Medicine, Hershey, PA

Genetics of PCOS
Women between the ages of 18 and 40 without serious health problems with 6 or fewer menstrual periods per year may be eligible to participate in a research study. You cannot be taking birth control pills or other hormones to be in the study.

The study is nationwide and will involve diagnostic testing and medical evaluation at no charge. You will receive a stipend for participating.

A 4-month Double-Blind Randomized Trial of Atorvastatin for the Treatment of PCOS Women with Elevated LDL-Cholesterol This research study is studying the use of the drug, atorvastatin, (Lipitor), to see if it will both lower blood cholesterol levels and improve the rate of ovulation in women with PCOS who have elevated LDL-cholesterol.

The purpose of the study is to determine the safety and efficacy of atorvastatin for the treatment of PCOS. We are looking for women with PCOS ages 18-40 with a fasting LDL-Cholesterol level above 100 mg/dL and elevated male hormone levels. The study involves traveling the Hershey Medical Center six times over a 4-month period. You will be assigned by chance to receive either 40 mg of atorvastatin or a placebo pill (inactive pill). The study will involve checkups every 4 weeks. Oral glucose tolerance tests will be done prior to and at completion of the study. All women will be monitored for side effects and pregnancy while on the medication.

For more information call 1-800-585-9585
Website: http://www.hmc.psu.edu/womens/research/pcos/index.html
End Date: 3/31/06

Rhode Island

South Carolina

South Dakota

Tennessee

Texas

Utah

Vermont

Virginia

Summary: UVa Health System Center for Research in Reproduction seeks Healthy Women ages 18 to 35 with and without Polycystic Ovarian Syndrome (PCOS) for Research Study

The purpose of the study is to investigate the effects of elevated insulin and androgen levels on the endometrium.  Healthy volunteers should have regular menstrual cycles.  Volunteers with PCOS should have a history of 6 menstrual cycles per year or less, as well as elevated testosterone levels and/or problems with increased hair growth.  Participants must not have taken birth control pills or hormonal medications for at least 3 months before the research study. The study involves a screening physical exam and blood work and a total of seven outpatient visits.  Three endometrial biopsies will be performed.  Study related visits and tests are provided at no charge.  Compensation for study completion is $200.

For more information, please contact:
Quirine Lamberts Okonkwo
(434)243-6911
pcos@virginia.edu
HIC# 8966

Primary Investigator:  Dr. John Marshall

Summary: UVa Health System Center for Research in Reproduction Seeks Women with Polycystic Ovarian Syndrome (PCOS) for Research Study

The purpose of the study is to investigate whether flutamide, estrogen, and progesterone can induce ovulation in women with PCOS.  Participants should have a history of less than 6 menstrual cycles per year, as well as elevated testosterone levels and/or problems with increased hair growth. Participants must not have taken birth control pills or hormonal medications for at least 3 months before the research study. Participants must be willing to avoid pregnancy through non-hormonal means of contraception throughout the duration of the study.  The study includes a screening physical exam and blood work, 10-15 outpatient visits, and 3 overnight admissions to the General Clinical Research Center over a period of 3-4 months.  Study related visits, tests, and medications are provided at no charge. A longer-term study is available for those who ovulate during this study.  No compensation is provided for this study.

For more information, please contact:
Quirine Lamberts Okonkwo
(434)243-6911
pcos@virginia.edu
HIC 5521

Primary Investigator:  Dr. John Marshall

Summary: UVa Health System Center for Research in Reproduction Seeks Healthy Women Ages 18 to 35 with and without Polycystic Ovarian Syndrome (PCOS) for Research Study

The purpose of the study is to investigate the effect of dihydrotestosterone on the hypothalamus and pituitary gland.  Healthy volunteers should have regular menstrual cycles.  PCOS volunteers should have a history of less than 6 menstrual cycles per year, as well as elevated testosterone levels and/or problems with increased hair growth. Participants must not have taken birth control pills or hormonal medications for at least 3 months before the research study. The study includes a screening physical exam and blood work, four outpatient visits, and 3 admissions to the General Clinical Research Center.  Study related visits and tests are provided at no charge. Compensation for study completion is $300 for healthy participants.  No compensation is provided for participants with PCOS.

For more information, please contact:
Quirine Lamberts Okonkwo
(434)243-6911
pcos@virginia.edu
HIC# 10842

Primary Investigator:  Dr. Chris McCartney

Washington

West Virginia

Wisconsin

Wyoming